On the lonely road two outcasts meet -- spitfire Doris and a genteel, shell-shocked dog. Each of this unlikely pair harbors heavy grief and must decide whether to stay with their pain or run from it. Their journey takes them through wild and empty lands, an eerily abandoned town of echoes, and out to "Mudder Sea", a mysterious realm of visions all-too-clear.

Malkasian's graphic novels are known for their layered metaphor, and Shadows of the Sea is no exception, with darkness itself a character, bearing the weight of unbearable truths.